CMS Callers for Clinical and Preclinical Applications

To simplify the testing of CMS we have developed a R shiny app using our published classifier.  The application can be found here as optimized for Nanostring platform.

The reference:

Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting

The underlying code is available here within the MD Anderson intranet.

 

For pre-clinical applications, we would recommend the following CMS caller which is not impacted by presence of nonhuman stroma, or absence of stroma.

CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models