PDX Resources and Profiling

400 models with clinical annotation and clinical molecular profile

>125 Annotated PDX Models by WES and RNA seq

cBioPortal database with PDX samples details. 

PDX Model Browser with Clinical Data

Also, for those inside MDACC, navigate to the Kopetz Lab Team in Microsoft Teams to explore

RNA Sequencing for PDX samples

Click the link for access to BOX folder for the RNA, with meta data for the samples, and the gencode V23 transcripts/genes used for mapping. There are matrices for counts, and TPMS for both transcripts and collapsed to genes.

DNA Sequencing for PDX samples

Click the link to access to BOX folder for the DNA. This file contains the corresponding .vcf calls from the vendor and the sample ID.

Please contact Scott Kopetz if you require access from external site to the BOX folder.  Many thanks to Chris Bristow and Justin Huang for their work on this.