{"id":49,"date":"2018-09-06T23:37:32","date_gmt":"2018-09-06T23:37:32","guid":{"rendered":"http:\/\/crcmoonshot.org\/?page_id=49"},"modified":"2022-02-16T01:00:06","modified_gmt":"2022-02-16T01:00:06","slug":"cms-multigene-signature","status":"publish","type":"page","link":"https:\/\/crcmoonshot.org\/?page_id=49","title":{"rendered":"CMS Multigene Signature"},"content":{"rendered":"<p>This shiny app is designed to evaluate differences in <strong>gene signatures<\/strong> between the CMS groups of single genes. \u00a0 The genes must be entered in using standard nomenclature and separated by a comma.\u00a0 Three datasets are available, including the proprietary internal Integromics dataset, a batch normalized set of Affymetric array data, and the TCGA. Three different methodologies are provided for generating the signatures.\u00a0 Links are provided for downloading the raw data and the image files.\u00a0 Please contact Gani Manyam (gcmanyam@mdanderson.org) if server is unavailable.<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" class=\"wp-image-219  aligncenter\" src=\"http:\/\/crcmoonshot.org\/wp-content\/uploads\/wordpress-administration-password-reset-300x300.png\" alt=\"\" width=\"66\" height=\"66\" srcset=\"https:\/\/crcmoonshot.org\/wp-content\/uploads\/wordpress-administration-password-reset-300x300.png 300w, https:\/\/crcmoonshot.org\/wp-content\/uploads\/wordpress-administration-password-reset-150x150.png 150w, https:\/\/crcmoonshot.org\/wp-content\/uploads\/wordpress-administration-password-reset.png 600w\" sizes=\"(max-width: 66px) 100vw, 66px\" \/><strong>Open Access<\/strong><\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/bioinformatics.mdanderson.org\/apps\/CMS_GeneSetAnalysis\/\">https:\/\/bioinformatics.mdanderson.org\/apps\/CMS_GeneSetAnalysis\/<\/a><\/p>\n<p><img loading=\"lazy\" class=\"alignnone size-large wp-image-51\" src=\"http:\/\/crcmoonshot.org\/wp-content\/uploads\/Screenshot_2018-09-06-CRC-Gene-Expression-CMS-subtypes1-1024x594.png\" alt=\"\" width=\"660\" height=\"383\" srcset=\"https:\/\/crcmoonshot.org\/wp-content\/uploads\/Screenshot_2018-09-06-CRC-Gene-Expression-CMS-subtypes1-1024x594.png 1024w, https:\/\/crcmoonshot.org\/wp-content\/uploads\/Screenshot_2018-09-06-CRC-Gene-Expression-CMS-subtypes1-300x174.png 300w, https:\/\/crcmoonshot.org\/wp-content\/uploads\/Screenshot_2018-09-06-CRC-Gene-Expression-CMS-subtypes1-768x445.png 768w\" sizes=\"(max-width: 660px) 100vw, 660px\" \/><\/p>\n<p>*This format can be achieved for larger gene sets by first exporting the list to an Excel files with genes listed in a single row, then\u00a0saving in a CSV format, and then opening with a text editor and copy\/pasting the resulting text file.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This shiny app is designed to evaluate differences in gene signatures between the CMS groups of single genes. \u00a0 The genes must be entered in using standard nomenclature and separated by a comma.\u00a0 Three datasets are available, including the proprietary internal Integromics dataset, a batch normalized set of Affymetric array data, and the TCGA. Three &hellip; <a href=\"https:\/\/crcmoonshot.org\/?page_id=49\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">CMS Multigene Signature<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/crcmoonshot.org\/index.php?rest_route=\/wp\/v2\/pages\/49"}],"collection":[{"href":"https:\/\/crcmoonshot.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/crcmoonshot.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/crcmoonshot.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/crcmoonshot.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=49"}],"version-history":[{"count":8,"href":"https:\/\/crcmoonshot.org\/index.php?rest_route=\/wp\/v2\/pages\/49\/revisions"}],"predecessor-version":[{"id":220,"href":"https:\/\/crcmoonshot.org\/index.php?rest_route=\/wp\/v2\/pages\/49\/revisions\/220"}],"wp:attachment":[{"href":"https:\/\/crcmoonshot.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=49"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}